Jump to main content
Jump to site search

Issue 74, 2014
Previous Article Next Article

A simple and efficient mechanochemical route for the synthesis of 2-aryl benzothiazoles and substituted benzimidazoles

Author affiliations

Abstract

An efficient and versatile mechanochemical route to 2-aryl benzothiazoles and both 2-substituted and 1,2-disubstituted benzimidazole derivatives has been developed via a simple mortar–pestle grinding method. The mechanochemical agitation was found to be sufficient for smooth condensation between a variety of aromatic aldehydes and o-aminothiophenol/o-phenylenediamine followed by cyclization leading to the formation of the corresponding 1,3-benzazoles. The salient features of this new protocol are catalyst-free reaction, cleaner reaction profiles, absence of a work-up step, high yields, and short reaction times.

Graphical abstract: A simple and efficient mechanochemical route for the synthesis of 2-aryl benzothiazoles and substituted benzimidazoles

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Jul 2014, accepted on 20 Aug 2014 and first published on 20 Aug 2014


Article type: Communication
DOI: 10.1039/C4RA07058E
Author version
available:
Download author version (PDF)
Citation: RSC Adv., 2014,4, 39606-39611
  •   Request permissions

    A simple and efficient mechanochemical route for the synthesis of 2-aryl benzothiazoles and substituted benzimidazoles

    M. Banerjee, A. Chatterjee, V. Kumar, Z. T. Bhutia, D. G. Khandare, M. S. Majik and B. G. Roy, RSC Adv., 2014, 4, 39606
    DOI: 10.1039/C4RA07058E

Search articles by author

Spotlight

Advertisements