Issue 1, 2014

An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

Abstract

An efficient method for the synthesis of spirooxindolopyrrolizidine/spirooxindolothiapyrrolizidine by the 1,3-dipolar cycloaddition of azomethine ylides generated via, decarboxylative condensation of 1,2-dicarbonyl compounds and L-proline/L-thiaproline/sarcosine with chalcones at ambient conditions with excellent yields has been described.

Graphical abstract: An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

Supplementary files

Article information

Article type
Paper
Submitted
23 Aug 2013
Accepted
06 Nov 2013
First published
07 Nov 2013

RSC Adv., 2014,4, 279-285

An efficient green chemistry protocol for the synthesis of novel spiropyrrolizidine compounds

K. Revathy and A. Lalitha, RSC Adv., 2014, 4, 279 DOI: 10.1039/C3RA44627A

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