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Issue 10, 2014
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Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

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Abstract

This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future.

Graphical abstract: Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

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Publication details

The article was received on 11 Jan 2014, accepted on 11 Feb 2014 and first published on 24 Mar 2014


Article type: Minireview
DOI: 10.1039/C4PY00039K
Citation: Polym. Chem., 2014,5, 3291-3297
  • Open access: Creative Commons BY license
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    Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

    A. Pitto-Barry and N. P. E. Barry, Polym. Chem., 2014, 5, 3291
    DOI: 10.1039/C4PY00039K

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