Issue 28, 2014
From the journal:

Organic & Biomolecular Chemistry

Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold†

Brian M. Muller,a   Jesse Mai,a   Reid A. Yocuma  and  Marc J. Adler*a  

* Corresponding authors

a Department of Chemistry & Biochemistry, Northern Illinois University, 1425 W Lincoln Hwy, DeKalb, IL, USA
E-mail: mjadler@niu.edu
Tel: +1 815 753 9236

Abstract

The effect of aryl substitution on various aspects of the interconversion of ortho-hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability for application as a functional colorimetric molecular switch.

Graphical abstract: Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold

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Article information

DOI
https://doi.org/10.1039/C4OB00398E
Article type
Paper
Submitted
20 Feb 2014
Accepted
28 Apr 2014
First published
06 May 2014

Org. Biomol. Chem., 2014,12, 5108-5114

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Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold

B. M. Muller, J. Mai, R. A. Yocum and M. J. Adler, Org. Biomol. Chem., 2014, 12, 5108 DOI: 10.1039/C4OB00398E

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