Issue 38, 2014
From the journal:

Organic & Biomolecular Chemistry

Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine†

Jing Zhoua  and  Ying-Yeung Yeung*a  

* Corresponding authors

a Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
E-mail: chmyyy@nus.edu.sg
Fax: (+)65 6779 1691
Tel: (+)65 6516 7760

Abstract

An efficient aziridine ring expansion cascade of cinnamylaziridine has been developed. N-Bromosuccinimide was used as the promoter. The resulting functionalized pyrrolidines are the fundamental units of many useful molecules.

Graphical abstract: Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine

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Article information

DOI
https://doi.org/10.1039/C4OB01384K
Article type
Communication
Submitted
02 Jul 2014
Accepted
06 Aug 2014
First published
06 Aug 2014
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2014,12, 7482-7485

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Diastereoselective synthesis of functionalized pyrrolidines through N-bromosuccinimide-induced aziridine ring expansion cascade of cinnamylaziridine

J. Zhou and Y. Yeung, Org. Biomol. Chem., 2014, 12, 7482 DOI: 10.1039/C4OB01384K

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