Jump to main content
Jump to site search

Issue 38, 2014
Previous Article Next Article

Recent developments in transition metal-catalysed spiroketalisation

Author affiliations

Abstract

The spiroketal motif occurs in a wide range of biologically active natural products and represents a valuable target in medicinal chemistry and total synthesis. In recent years, innovative new synthetic methods have substantially expanded the range of potential precursors, cyclisation modes and opportunities for asymmetric catalysis and tandem processes. This Perspective aims to highlight recent rapid advances in the use of transition metal catalysis for spiroketal formation, in the context of our own investigations into gold-catalysed asymmetric spiroketalisation.

Graphical abstract: Recent developments in transition metal-catalysed spiroketalisation

Back to tab navigation

Publication details

The article was received on 26 Jun 2014, accepted on 12 Aug 2014 and first published on 13 Aug 2014


Article type: Perspective
DOI: 10.1039/C4OB01325E
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2014,12, 7423-7432
  •   Request permissions

    Recent developments in transition metal-catalysed spiroketalisation

    R. Quach, D. F. Chorley and M. A. Brimble, Org. Biomol. Chem., 2014, 12, 7423
    DOI: 10.1039/C4OB01325E

Search articles by author

Spotlight

Advertisements