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Discovery and SAR study of piperidine-based derivatives as novel influenza virus inhibitors

Guoxin Wang,*a   Longjian Chen,a   Tongmei Xian,a   Yujie Liang,a   Xintao Zhang,b   Zhen Yang*a and   Ming Luo*ac  
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a
Key Laboratory of Structural Biology and Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China
E-mail: wanggx@pkusz.edu.cn, zyang@pku.edu.cn, mluo@gsu.edu
b
Urology Department, Shenzhen Second People's Hospital, Shenzhen, China
c
Department of Chemistry, Georgia State University, Atlanta, USA
Org. Biomol. Chem., 2014,12, 8048-8060

DOI: 10.1039/C4OB01079E
Received 26 May 2014, Accepted 06 Aug 2014
First published online 07 Aug 2014
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