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Issue 27, 2014
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Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

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Abstract

Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

Graphical abstract: Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

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Publication details

The article was received on 10 May 2014, accepted on 30 May 2014 and first published on 30 May 2014


Article type: Communication
DOI: 10.1039/C4OB00970C
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2014,12, 4828-4831
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    Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

    S. Huang, L. Ma, M. H. Tong, Y. Yu, D. O'Hagan and H. Deng, Org. Biomol. Chem., 2014, 12, 4828
    DOI: 10.1039/C4OB00970C

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