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Issue 31, 2014
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Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units

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Abstract

Diketopiperazine (DKP) units are found in many bioactive small molecules. Here we report facile chemistry for incorporating diverse DKP units within peptoid and peptoid-like libraries made by solid-phase split and pool synthesis.

Graphical abstract: Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units

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Publication details

The article was received on 22 Apr 2014, accepted on 23 Jun 2014 and first published on 30 Jun 2014


Article type: Communication
DOI: 10.1039/C4OB00829D
Citation: Org. Biomol. Chem., 2014,12, 5831-5834
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    Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units

    S. Suwal and T. Kodadek, Org. Biomol. Chem., 2014, 12, 5831
    DOI: 10.1039/C4OB00829D

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