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Issue 22, 2014
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Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

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Abstract

Continuous flow chemistry as a process intensification tool is well known. However, its ability to enable chemists to perform reactions which are not possible in batch is less well studied or understood. Here we present an example, where a new reactivity pattern and extended reaction scope has been achieved by transferring a reaction from batch mode to flow. This new reactivity can be explained by suppressing back mixing and precise control of temperature in a flow reactor set up.

Graphical abstract: Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

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Publication details

The article was received on 28 Mar 2014, accepted on 17 Apr 2014 and first published on 17 Apr 2014


Article type: Paper
DOI: 10.1039/C4OB00662C
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Citation: Org. Biomol. Chem., 2014,12, 3611-3615
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    Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

    J. Hartwig, J. B. Metternich, N. Nikbin, A. Kirschning and S. V. Ley, Org. Biomol. Chem., 2014, 12, 3611
    DOI: 10.1039/C4OB00662C

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