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Issue 24, 2014
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Versatile post-functionalization of the external shell of cowpea chlorotic mottle virus by using click chemistry

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Abstract

We present the modification of the outer protein shell of cowpea chlorotic mottle virus (CCMV) with linear and strained alkyne groups. These functionalized protein capsids constitute valuable platforms for post-functionalization via click chemistry. After modification, the integrity of the capsid and the reversible disassembly behavior are preserved.

Graphical abstract: Versatile post-functionalization of the external shell of cowpea chlorotic mottle virus by using click chemistry

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Publication details

The article was received on 06 Mar 2014, accepted on 29 Apr 2014 and first published on 09 May 2014


Article type: Communication
DOI: 10.1039/C4OB00505H
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2014,12, 4065-4069
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    Versatile post-functionalization of the external shell of cowpea chlorotic mottle virus by using click chemistry

    C. A. Hommersom, B. Matt, A. van der Ham, J. J. L. M. Cornelissen and N. Katsonis, Org. Biomol. Chem., 2014, 12, 4065
    DOI: 10.1039/C4OB00505H

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