Jump to main content
Jump to site search

Issue 27, 2014
Previous Article Next Article

An easy route to synthetic analogues of radicamine B, codonopsine and codonopsinine from D-mannitol

Author affiliations

Abstract

A general strategy for the synthesis of analogues of radicamine B has been carried out from D-mannitol. This method has been further extended to the synthesis of analogues of codonopsine and codonopsinine using appropriate Grignard reagents. The hence obtained molecules have been tested against various commercially available glycosidases and found to act as moderate to good inhibitors.

Graphical abstract: An easy route to synthetic analogues of radicamine B, codonopsine and codonopsinine from d-mannitol

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Mar 2014, accepted on 17 Apr 2014 and first published on 17 Apr 2014


Article type: Paper
DOI: 10.1039/C4OB00503A
Citation: Org. Biomol. Chem., 2014,12, 4983-4998
  •   Request permissions

    An easy route to synthetic analogues of radicamine B, codonopsine and codonopsinine from D-mannitol

    S. Dharuman, A. K. Palanivel and Y. D. Vankar, Org. Biomol. Chem., 2014, 12, 4983
    DOI: 10.1039/C4OB00503A

Search articles by author

Spotlight

Advertisements