Our website is evolving and our goal is to create a great user experience for our readers and authors. You will see regular enhancements to our site in the coming months.
Please visit our news site for further information.
Three novel analogues of the cyclic pentapeptide sansalvamide A have been synthesised in high yield. A leucine residue in the lead compound is replaced with either a glycine, β-alanine or GABA residue, and the corresponding linear precursor peptides are found to cyclise with dramatically improved efficiency. This correlates with an increase in the effective molarity (EM) of the cyclisation reactions.
Fetching data from CrossRef. This may take some time to load.