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Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors

Jian-Peng Yin,a   Chun-Lan Tang,b   Li-Xin Gao,b   Wei-Ping Ma,b   Jing-Ya Li,b   Ying Li,*a   Jia Li*b and   Fa-Jun Nan*b  
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State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P.R. China
The National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P.R. China
Org. Biomol. Chem., 2014,12, 3441-3445

DOI: 10.1039/C4OB00214H
Received 27 Jan 2014, Accepted 24 Mar 2014
First published online 25 Mar 2014
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