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Issue 17, 2014
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Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

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Abstract

The interest in the functionalization of oligonucleotides with organic molecules has grown considerably over the last decade. In this work, we report on the synthesis and characterization of porphyrin–oligonucleotide hybrids containing one to four DNA strands (P1–P4). The hybrid P4, which inserts one porphyrin and four DNA fragments, was combined with gold nanoparticles and imaged by transmission electron microscopy.

Graphical abstract: Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

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Publication details

The article was received on 25 Jan 2014, accepted on 25 Feb 2014 and first published on 25 Feb 2014


Article type: Paper
DOI: 10.1039/C4OB00202D
Author version available: Download Author version (PDF)
Citation: Org. Biomol. Chem., 2014,12, 2778-2783
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    Synthesis of a multibranched porphyrin–oligonucleotide scaffold for the construction of DNA-based nano-architectures

    G. Clavé, G. Chatelain, A. Filoramo, D. Gasparutto, C. Saint-Pierre, E. Le Cam, O. Piétrement, V. Guérineau and S. Campidelli, Org. Biomol. Chem., 2014, 12, 2778
    DOI: 10.1039/C4OB00202D

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