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Issue 14, 2014
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Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide

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Abstract

A strategy for the stereoselective functionalization of thietane 1-oxide has been developed. Mono (C2 substituted) and doubly (C2, C4 disubstituted) functionalized thietanes have been obtained from the readily available thietane 1-oxide by using the corresponding organometallic intermediates that reacted with electrophiles leaving intact the 4-membered ring.

Graphical abstract: Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide

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Publication details

The article was received on 22 Jan 2014, accepted on 11 Feb 2014 and first published on 12 Feb 2014


Article type: Communication
DOI: 10.1039/C4OB00173G
Citation: Org. Biomol. Chem., 2014,12, 2180-2184
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    Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide

    L. Carroccia, L. Degennaro, G. Romanazzi, C. Cuocci, L. Pisano and R. Luisi, Org. Biomol. Chem., 2014, 12, 2180
    DOI: 10.1039/C4OB00173G

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