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Issue 24, 2014
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A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

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Abstract

A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.

Graphical abstract: A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

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Publication details

The article was received on 21 Jan 2014, accepted on 02 May 2014 and first published on 05 May 2014


Article type: Communication
DOI: 10.1039/C4OB00160E
Citation: Org. Biomol. Chem., 2014,12, 4089-4092
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    A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

    F. Taraballi, L. Russo, C. Battocchio, G. Polzonetti, F. Nicotra and L. Cipolla, Org. Biomol. Chem., 2014, 12, 4089
    DOI: 10.1039/C4OB00160E

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