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Organocatalytic [4 + 2] cyclocondensation of α,β-unsaturated acyl chlorides with imines: highly enantioselective synthesis of dihydropyridinone and piperidine derivatives

Wen-Qiang Jia,a   Xiang-Yu Chen,a   Li-Hui Suna and   Song Ye*a  
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Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: songye@iccas.ac.cn;
Fax: +86-10-62554449
Org. Biomol. Chem., 2014,12, 2167-2171

DOI: 10.1039/C4OB00114A
Received 15 Jan 2014, Accepted 13 Feb 2014
First published online 13 Feb 2014
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