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Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of β-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitols

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a
Oxford Glycobiology Institute, University of Oxford, South Parks Road, Oxford, UK ;
Fax: +44 (0)1865 275216 ;
Tel: +44 (0)1865 275342
b
Chemistry Research Laboratory, 12 Mansfield Road, Oxford, UK
E-mail: Andreas.Glawar@chem.oxon.org;
Fax: +44 (0)1865 285002 ;
Tel: +44 (0)1865 275645
c
Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
E-mail: kato@med.u-toyama.ac.uk
d
Departamento de Química Orgánica e Inorgánica, QUOREX Research Group, Universidad de Extremadura, Avda. Elvas s/n, E-06006 Badajoz, Spain
Org. Biomol. Chem., 2014,12, 3932-3943

DOI: 10.1039/C4OB00097H
Received 13 Jan 2014, Accepted 01 Apr 2014
First published online 02 Apr 2014
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