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Paper

Structure-based de novo design and identification of D816V mutant-selective c-KIT inhibitors

Hwangseo Park,*a   Soyoung Lee,b   Suhyun Leeb and   Sungwoo Hong*b  
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a
Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea
E-mail: hspark@sejong.ac.kr;
Fax: (+82) 2-3408-3766 ;
Tel: (+82) 2-3408-2811
b
Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea
E-mail: hongorg@kaist.ac.kr;
Fax: (+82) 42-350-2810 ;
Tel: (+82) 42-350-2811
Org. Biomol. Chem., 2014,12, 4644-4655

DOI: 10.1039/C4OB00053F
Received 08 Jan 2014, Accepted 30 Jan 2014
First published online 22 May 2014
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