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Review Article

The development of catalytic nucleophilic substitution reactions: challenges, progress and future directions

Jie An,a   Ross M. Denton,*a   Tristan H. Lambert*b and   Eric D. Nacsab  
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a
School of Chemistry, University Park, Nottingham, UK
E-mail: ross.denton@nottinghaqm.ac.uk;
Fax: +44 (0)1159513555 ;
Tel: +44 (0)1159414194
b
Columbia University, Department of Chemistry, Broadway, New York, USA
E-mail: tl2240@columbia.edu;
Fax: +1 212 932 1289 ;
Tel: +1 212 854 1438
Org. Biomol. Chem., 2014,12, 2993-3003

DOI: 10.1039/C4OB00032C
Received 06 Jan 2014, Accepted 24 Mar 2014
First published online 25 Mar 2014
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