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Issue 14, 2014
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Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins

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Abstract

The tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles has been developed and the biologically important indole-3-substituted dihydrocoumarins were obtained in good to excellent yields under catalyst-free conditions.

Graphical abstract: Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins

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Publication details

The article was received on 25 Dec 2013, accepted on 03 Feb 2014 and first published on 03 Feb 2014


Article type: Communication
DOI: 10.1039/C3OB42582G
Citation: Org. Biomol. Chem., 2014,12, 2185-2188
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    Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins

    Z. Shao, L. Xu, L. Wang, H. Wei and J. Xiao, Org. Biomol. Chem., 2014, 12, 2185
    DOI: 10.1039/C3OB42582G

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