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Issue 25, 2014
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A highly efficient catalyst of a nitrogen-based ligand for the Suzuki coupling reaction at room temperature under air in neat water

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Abstract

Glycine, as a kind of commercially available and inexpensive ligand, is used to prepare an air-stable and water-soluble catalyst for the Suzuki–Miyaura reaction in our study. In the presence of 0.1% [PdCl2(NH2CH2COOH)2] as the catalyst, extremely excellent catalytic activity towards the Suzuki–Miyaura coupling of aryl halides containing the carboxyl group with various aryl boronic acids is observed at room temperature under air in neat water.

Graphical abstract: A highly efficient catalyst of a nitrogen-based ligand for the Suzuki coupling reaction at room temperature under air in neat water

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Publication details

The article was received on 18 Dec 2013, accepted on 21 Apr 2014 and first published on 22 Apr 2014


Article type: Paper
DOI: 10.1039/C3OB42517G
Citation: Org. Biomol. Chem., 2014,12, 4511-4516
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    A highly efficient catalyst of a nitrogen-based ligand for the Suzuki coupling reaction at room temperature under air in neat water

    S. Liu, M. Lv, D. Xiao, X. Li, X. Zhou and M. Guo, Org. Biomol. Chem., 2014, 12, 4511
    DOI: 10.1039/C3OB42517G

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