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Base mediated synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones from 2-aminobenzonitriles and aromatic aldehydes in water

Xiao-Feng Wu,*ab   Stefan Oschatz,bc   Axel Block,bc   Anke Spannenbergb and   Peter Langer*bc  
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Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, People's Republic of China
Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Str. 29a, 18059 Rostock, Germany
Universität Rostock, Institut für Chemie, Albert-Einstein-Str. 3a, Rostock, Germany
Org. Biomol. Chem., 2014,12, 1865-1870

DOI: 10.1039/C3OB42434K
Received 05 Dec 2013, Accepted 23 Jan 2014
First published online 23 Jan 2014
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