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Concise and scalable asymmetric synthesis of 5-(1-amino-2,2,2-trifluoroethyl)thiazolo[3,2-b][1,2,4]triazoles

Haibo Mei,ab   Yiwen Xiong,a   Chen Xie,a   Vadim A. Soloshonok,cd   Jianlin Han*abe and   Yi Pana  
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a
School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
E-mail: hanjl@nju.edu.cn;
Fax: +86-25-83593153 ;
Tel: +86-25-83593153
b
Institute for Chemistry & BioMedical Sciences, Nanjing University, Nanjing, China
c
Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, San Sebastian, Spain
d
IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain
e
High-Tech Research Institute of Nanjing University, Changzhou, China
Org. Biomol. Chem., 2014,12, 2108-2113

DOI: 10.1039/C3OB42348D
Received 24 Nov 2013, Accepted 29 Jan 2014
First published online 29 Jan 2014
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