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Issue 3, 2014
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Et4NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

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Abstract

An efficient method for the oxidative amidation of benzylic aldehydes or alcohols with ammonium salts has been developed for the synthesis of primary amides using Et4NI as the catalyst and tert-butyl hydroperoxide as the oxidant. This amidation reaction is operationally straightforward and provides primary amides in moderate to good yields under mild conditions.

Graphical abstract: Et4NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

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Publication details

The article was received on 11 Oct 2013, accepted on 05 Nov 2013 and first published on 07 Nov 2013


Article type: Communication
DOI: 10.1039/C3OB42037J
Citation: Org. Biomol. Chem., 2014,12, 414-417
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    Et4NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

    G. Wang, Q. Yu, S. Chen and X. Yu, Org. Biomol. Chem., 2014, 12, 414
    DOI: 10.1039/C3OB42037J

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