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NHC-catalyzed oxidative γ-addition of α,β-unsaturated aldehydes to isatins: a high-efficiency synthesis of spirocyclic oxindole-dihydropyranones

Rui Liu,a   Chenxia Yu,a   Zhaoxin Xiao,a   Tuanjie Li,a   Xiangshan Wang,a   Yuanwei Xiea and   Changsheng Yao*b  
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Corresponding authors
a
School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China
b
School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Jiangsu Normal University, Xuzhou, P. R. China
E-mail: csyao@jsnu.edu.cn
Org. Biomol. Chem., 2014,12, 1885-1891

DOI: 10.1039/C3OB42008F
Received 05 Oct 2013, Accepted 30 Dec 2013
First published online 06 Jan 2014
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