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NHC-catalyzed oxidative γ-addition of α,β-unsaturated aldehydes to isatins: a high-efficiency synthesis of spirocyclic oxindole-dihydropyranones

Rui Liu,a   Chenxia Yu,a   Zhaoxin Xiao,a   Tuanjie Li,a   Xiangshan Wang,a   Yuanwei Xiea and   Changsheng Yao*b  
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School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, P. R. China
School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Jiangsu Normal University, Xuzhou, P. R. China
Org. Biomol. Chem., 2014,12, 1885-1891

DOI: 10.1039/C3OB42008F
Received 05 Oct 2013, Accepted 30 Dec 2013
First published online 06 Jan 2014
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