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Rapid access to α-carbolines via a one-pot tandem reaction of α,β-unsaturated ketones with 2-nitrophenylacetonitrile and the anti-proliferative activities of the products

Xiaofei Zhang,a   Qian He,a   Haoyue Xiang,a   Shanshan Song,a   Zehong Miao*a and   Chunhao Yang*a  
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a
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai, 201203, P.R. China
E-mail: zhmiao@simm.ac.cn, chyang@simm.ac.cn;
Fax: +86-21-50806820 ;
Tel: +86-21-50806820
Org. Biomol. Chem., 2014,12, 355-361

DOI: 10.1039/C3OB41921E
Received 22 Sep 2013, Accepted 05 Nov 2013
First published online 05 Nov 2013
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