Jump to main content
Jump to site search

Issue 13, 2014
Previous Article Next Article

In vitro dosimetry of agglomerates

Author affiliations

Abstract

Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computational model of dosimetry. The approach used here paves the way for a better understanding of the impact of agglomeration on the nanoparticle–cell interaction.

Graphical abstract: In vitro dosimetry of agglomerates

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Jan 2014, accepted on 17 Apr 2014 and first published on 21 Apr 2014


Article type: Paper
DOI: 10.1039/C4NR00460D
Author version available: Download Author version (PDF)
Citation: Nanoscale, 2014,6, 7325-7331
  •   Request permissions

    In vitro dosimetry of agglomerates

    V. Hirsch, C. Kinnear, L. Rodriguez-Lorenzo, C. A. Monnier, B. Rothen-Rutishauser, S. Balog and A. Petri-Fink, Nanoscale, 2014, 6, 7325
    DOI: 10.1039/C4NR00460D

Search articles by author

Spotlight

Advertisements