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Issue 6, 2014
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Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

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Abstract

Copper sulphides, as a novel kind of photothermal agent for photothermal therapy (PTT) of cancer cells, have attracted increasing attention in recent years due to good photostability, synthetic simplicity, low toxicity and low cost. However, the unsatisfactory photothermal conversion efficiency of copper sulphides limits their bioapplication as PTT agents. Herein, Cu7.2S4 NCs with a mean size of ∼20 nm as a novel photothermal agent have been prepared by a simple thermal decomposition route. Moreover, these NCs exhibit strong near-infrared (NIR) absorption, good photostability and significant photothermal conversion efficiency up to 56.7% due to strong NIR absorption, good dispersity and suitable size. Importantly, these NCs can be very compatibly used as a 980 nm laser-driven PTT agent for the efficient PTT of cancer cells in vitro and in vivo.

Graphical abstract: Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

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Publication details

The article was received on 25 Nov 2013, accepted on 02 Jan 2014 and first published on 08 Jan 2014


Article type: Paper
DOI: 10.1039/C3NR06242B
Citation: Nanoscale, 2014,6, 3274-3282
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    Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

    B. Li, Q. Wang, R. Zou, X. Liu, K. Xu, W. Li and J. Hu, Nanoscale, 2014, 6, 3274
    DOI: 10.1039/C3NR06242B

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