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Issue 16, 2014
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Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

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Abstract

A versatile gold nanoparticle-based multifunctional RB-DEVD-AuNP-DTP has been developed to induce the targeted apoptosis of cancer cells and image in real time the progress of the apoptosis. The multifunctional nanoparticles were demonstrated to have the ability to initiate mitochondria-dependent apoptosis and activate caspase-3 for real-time imaging of the progression of apoptosis.

Graphical abstract: Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

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Publication details

The article was received on 09 May 2014, accepted on 12 Jun 2014 and first published on 13 Jun 2014


Article type: Communication
DOI: 10.1039/C4NR02516D
Citation: Nanoscale, 2014,6, 9531-9535
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    Cancer-targeted functional gold nanoparticles for apoptosis induction and real-time imaging based on FRET

    W. Chen, G. Luo, X. Xu, H. Jia, Q. Lei, K. Han and X. Zhang, Nanoscale, 2014, 6, 9531
    DOI: 10.1039/C4NR02516D

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