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Issue 2, 2014
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Highly magnetic iron carbide nanoparticles as effective T2 contrast agents

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Abstract

This paper reports that iron carbide nanoparticles with high air-stability and strong saturation magnetization can serve as effective T2 contrast agents for magnetic resonance imaging. Fe5C2 nanoparticles (∼20 nm in diameter) exhibit strong contrast enhancement with an r2 value of 283.2 mM−1 S−1, which is about twice as high as that of spherical Fe3O4 nanoparticles (∼140.9 mM−1 S−1). In vivo experiments demonstrate that Fe5C2 nanoparticles are able to produce much more significant MRI contrast enhancement than conventional Fe3O4 nanoparticles in living subjects, which holds great promise in biomedical applications.

Graphical abstract: Highly magnetic iron carbide nanoparticles as effective T2 contrast agents

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Publication details

The article was received on 03 Sep 2013, accepted on 05 Nov 2013 and first published on 08 Nov 2013


Article type: Communication
DOI: 10.1039/C3NR04691E
Citation: Nanoscale, 2014,6, 726-730
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    Highly magnetic iron carbide nanoparticles as effective T2 contrast agents

    G. Huang, J. Hu, H. Zhang, Z. Zhou, X. Chi and J. Gao, Nanoscale, 2014, 6, 726
    DOI: 10.1039/C3NR04691E

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