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Issue 9, 2014
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Natural products containing ‘decalin’ motif in microorganisms

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Abstract

Covering: up to February 2014

Microorganisms are well-known producers of a wide variety of bioactive compounds that are utilized not only for their primary metabolism but also for other purposes such as defense, detoxification, or communication with other micro- and macro-organisms. Natural products containing a ‘decalin ring’ occur often in microorganisms. They exhibit diverse and remarkable biological activities, including antifungal, antibacterial, anticancer and immunosuppressive activities, to name a few. This review surveys the natural decalin-type compounds that have been isolated from microorganisms, with emphasis on both chemical and biological implications. Total syntheses of some important decalin moiety-containing natural products are also highlighted.

Graphical abstract: Natural products containing ‘decalin’ motif in microorganisms

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Publication details

The article was received on 19 Mar 2014 and first published on 02 Jul 2014


Article type: Review Article
DOI: 10.1039/C4NP00031E
Citation: Nat. Prod. Rep., 2014,31, 1175-1201
  • Open access: Creative Commons BY-NC license
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    Natural products containing ‘decalin’ motif in microorganisms

    G. Li, S. Kusari and M. Spiteller, Nat. Prod. Rep., 2014, 31, 1175
    DOI: 10.1039/C4NP00031E

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