Jump to main content
Jump to site search

Issue 6, 2014
Previous Article Next Article

Emerging capabilities of mass spectrometry for natural products

Author affiliations

Abstract

Covering up to the end of 2013

A brief history of mass spectrometry in natural products research serves to identify themes which have driven progress in this area of application and in mass spectrometry itself. This account covers six decades of ionization methods, starting with traditional electron ionization and progressing through today's ambient ionization methods. Corresponding developments in mass analyzers are indicated, ranging from sector magnetic fields, through hybrid quadrupole mass filters to miniature ion traps. Current capabilities of mass spectrometry in natural products studies include direct in situ analysis, mass spectrometry imaging, and the study of biosynthetic pathways using metabolomic information. The survey concludes with a discussion of new experiments and capabilities including ion soft landing, preparative mass spectrometry, and accelerated ionic reactions in confined volumes.

Graphical abstract: Emerging capabilities of mass spectrometry for natural products

Back to tab navigation

Publication details

The article was received on 13 Nov 2013 and first published on 03 Apr 2014


Article type: Highlight
DOI: 10.1039/C3NP70121B
Citation: Nat. Prod. Rep., 2014,31, 730-738
  •   Request permissions

    Emerging capabilities of mass spectrometry for natural products

    A. K. Jarmusch and R. G. Cooks, Nat. Prod. Rep., 2014, 31, 730
    DOI: 10.1039/C3NP70121B

Search articles by author

Spotlight

Advertisements