Issue 3, 2015

Aqueous intramolecular Mizoroki–Heck reaction of (2-iodophenyl)(3-methyl-1H-indol-1-yl)methanone: a model reaction for the in situ performance evaluation of Pd catalysts

Abstract

The regiospecific 5-exo intramolecular Mizoroki–Heck reaction of (2-iodophenyl)(3-methyl-1H-indol-1-yl)methanone is presented as a catalytic model reaction for the in situ performance evaluation of Pd catalysts for C–C cross-coupling reactions in aqueous medium. The reaction produces a conjugated cyclic compound which can be easily detected and quantified by UV-vis spectroscopy. Therefore, the reaction progress can be easily monitored and the catalytic parameters determined. The model reaction was tested using molecular and nanoparticulate catalysts, based on the Pd(OAc)2 salt.

Graphical abstract: Aqueous intramolecular Mizoroki–Heck reaction of (2-iodophenyl)(3-methyl-1H-indol-1-yl)methanone: a model reaction for the in situ performance evaluation of Pd catalysts

Supplementary files

Article information

Article type
Letter
Submitted
31 Oct 2014
Accepted
17 Dec 2014
First published
18 Dec 2014

New J. Chem., 2015,39, 1574-1578

Aqueous intramolecular Mizoroki–Heck reaction of (2-iodophenyl)(3-methyl-1H-indol-1-yl)methanone: a model reaction for the in situ performance evaluation of Pd catalysts

A. M. Signori, E. Latocheski, B. L. Albuquerque, D. Faggion, T. B. Bisol, L. Meier and J. B. Domingos, New J. Chem., 2015, 39, 1574 DOI: 10.1039/C4NJ01921K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements