Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 11, 2014
Previous Article Next Article

Bioinspired nanoarchitectonics as emerging drug delivery systems

Author affiliations

Abstract

We propose an important paradigm shift in the preparation of functional materials with well-designed nanostructures, from the nanotechnological to the nanoarchitectonic approach. Nanoarchitectonics is a methodology for arranging nanoscale structural units in the required configurations for new functional materials by the sophisticated combination and harmonization of several processes including atom/molecule manipulation, chemical nanomanipulation, field-induced materials control and controlled supramolecular self-assembly. In particular, nanoarchitectonics bears features of nanoscale phenomena including their flexibility and uncertainty of structure due to the unavoidable influence of thermal fluctuation. It shares characteristics with structural constructions in biological systems and could become a powerful bioinspired approach for materials science. Here, we focus on examples involving drug delivery functions due to these promising applications of bioinspired materials research. We commence with a discussion of recent developments involving assemblies of small amphiphilic molecules, polymer micelles and molecular conjugates and follow this with examples of challenging concepts including inorganic nanostructure design for drug delivery and mechanically controlled drug release. The new concept of bioinspired nanoarchitectonics could significantly expand the possibilities of systems design for drug delivery.

Graphical abstract: Bioinspired nanoarchitectonics as emerging drug delivery systems

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 26 May 2014, accepted on 17 Jul 2014 and first published on 17 Jul 2014


Article type: Perspective
DOI: 10.1039/C4NJ00864B
Citation: New J. Chem., 2014,38, 5149-5163
  •   Request permissions

    Bioinspired nanoarchitectonics as emerging drug delivery systems

    K. Ariga, K. Kawakami, M. Ebara, Y. Kotsuchibashi, Q. Ji and J. P. Hill, New J. Chem., 2014, 38, 5149
    DOI: 10.1039/C4NJ00864B

Search articles by author