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Issue 4, 2014
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In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

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Abstract

The synthesis of primary aminoquinolines from iodoquinolines was carried out in the presence of copper(I) iodide and formamide as the solvent and source of ammonia generated in situ. The reaction proceeded under mild conditions within a few hours and was applicable to various iodoquinolines.

Graphical abstract: In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

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Publication details

The article was received on 09 Jan 2014, accepted on 10 Feb 2014 and first published on 03 Mar 2014


Article type: Letter
DOI: 10.1039/C4NJ00046C
Author version available: Download Author version (PDF)
Citation: New J. Chem., 2014,38, 1389-1391
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    In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines

    A. Aillerie, S. Pellegrini, T. Bousquet and L. Pélinski, New J. Chem., 2014, 38, 1389
    DOI: 10.1039/C4NJ00046C

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