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Issue 11, 2014
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Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster

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Abstract

Arsenic-containing hydrocarbons (AsHC) constitute one group of arsenolipids that have been identified in seafood. In this first in vivo toxicity study for AsHCs, we show that AsHCs exert toxic effects in Drosophila melanogaster in a concentration range similar to that of arsenite. In contrast to arsenite, however, AsHCs cause developmental toxicity in the late developmental stages of Drosophila melanogaster. This work illustrates the need for a full characterisation of the toxicity of AsHCs in experimental animals to finally assess the risk to human health related to the presence of arsenolipids in seafood.

Graphical abstract: Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster

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Publication details

The article was received on 19 Sep 2014, accepted on 29 Sep 2014, published on 29 Sep 2014 and first published online on 29 Sep 2014


Article type: Communication
DOI: 10.1039/C4MT00249K
Citation: Metallomics, 2014,6, 2010-2014
  • Open access: Creative Commons BY license
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    Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster

    S. Meyer, J. Schulz, A. Jeibmann, M. S. Taleshi, F. Ebert, K. A. Francesconi and T. Schwerdtle, Metallomics, 2014, 6, 2010
    DOI: 10.1039/C4MT00249K

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