Jump to main content
Jump to site search

Issue 5, 2014
Previous Article Next Article

Lab-in-a-pen: a diagnostics format familiar to patients for low-resource settings

Author affiliations

Abstract

We present a low cost, simple and integrated device for medical diagnostics in low-resource settings called the lab-in-a-pen. Finger pricking, and sample collection and processing, are integrated with commercially available paper-based assays in a pen format. This approach ensures safety (i.e. biological sample and sharps containment) and can be used by untrained end users across multiple settings. The pen format also leverages existing low cost, high volume manufacturing and assembly methods. We characterize sample wicking in the lab-in-a-pen using porcine whole blood. The clinical diagnostic utility and usability of the lab-in-a-pen is established by testing of patients for Hepatitis B surface antigen (HBsAg) and Hepatitis B ā€˜eā€™ antigen (HBeAg) by medical staff at the National Hospital for Tropical Diseases in Hanoi, Vietnam.

Graphical abstract: Lab-in-a-pen: a diagnostics format familiar to patients for low-resource settings

Back to tab navigation

Publication details

The article was received on 17 Oct 2013, accepted on 23 Dec 2013 and first published on 02 Jan 2014


Article type: Paper
DOI: 10.1039/C3LC51185E
Citation: Lab Chip, 2014,14, 957-963
  •   Request permissions

    Lab-in-a-pen: a diagnostics format familiar to patients for low-resource settings

    M. M. Gong, B. D. MacDonald, T. V. Nguyen, K. Van Nguyen and D. Sinton, Lab Chip, 2014, 14, 957
    DOI: 10.1039/C3LC51185E

Search articles by author

Spotlight

Advertisements