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Issue 6, 2014
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Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: a convenient and efficient route to sulfonated oxindoles

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Abstract

A simple, efficient and catalyst-free procedure has been developed for the construction of sulfonated oxindoles via the direct arylsulfonylation of N-arylacrylamides with sulfinic acids. The present protocol, which simply utilizes cheap oxidants, readily-available starting materials, and catalyst-free conditions, provides an alternative and highly attractive approach to a series of sulfonated oxindoles with high atom efficiency and excellent functional group tolerance.

Graphical abstract: Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: a convenient and efficient route to sulfonated oxindoles

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Publication details

The article was received on 12 Feb 2014, accepted on 15 Mar 2014 and first published on 18 Mar 2014


Article type: Communication
DOI: 10.1039/C4GC00231H
Author version available: Download Author version (PDF)
Citation: Green Chem., 2014,16, 2988-2991
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    Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: a convenient and efficient route to sulfonated oxindoles

    W. Wei, J. Wen, D. Yang, J. Du, J. You and H. Wang, Green Chem., 2014, 16, 2988
    DOI: 10.1039/C4GC00231H

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