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Volume 172, 2014
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Boron doped diamond biotechnology: from sensors to neurointerfaces

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Abstract

Boron doped nanocrystalline diamond is known as a remarkable material for the fabrication of sensors, taking advantage of its biocompatibility, electrochemical properties, and stability. Sensors can be fabricated to directly probe physiological species from biofluids (e.g. blood or urine), as will be presented. In collaboration with electrophysiologists and biologists, the technology was adapted to enable structured diamond devices such as microelectrode arrays (MEAs), i.e. common electrophysiology tools, to probe neuronal activity distributed over large populations of neurons or embryonic organs. Specific MEAs can also be used to build neural prostheses or implants to compensate function losses due to lesions or degeneration of parts of the central nervous system, such as retinal implants, which exhibit real promise as biocompatible neuroprostheses for in vivo neuronal stimulations. New electrode geometries enable high performance electrodes to surpass more conventional materials for such applications.

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Publication details

The article was received on 14 Mar 2014, accepted on 14 Apr 2014 and first published on 06 May 2014


Article type: Paper
DOI: 10.1039/C4FD00040D
Author version available: Download Author version (PDF)
Citation: Faraday Discuss., 2014,172, 47-59
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    Boron doped diamond biotechnology: from sensors to neurointerfaces

    C. Hébert, E. Scorsone, A. Bendali, R. Kiran, M. Cottance, H. A. Girard, J. Degardin, E. Dubus, G. Lissorgues, L. Rousseau, P. Mailley, S. Picaud and P. Bergonzo, Faraday Discuss., 2014, 172, 47
    DOI: 10.1039/C4FD00040D

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