Issue 11, 2015

Towards the elaboration of new gold-based optical theranostics

Abstract

Four new red BODIPY–gold(I) theranostic compounds were synthesized. Some of them were vectorized by tethering a biovector (glucose or bombesin derivatives) to the metallic center. Their photophysical properties were studied. Additionally, their cytotoxicity was examined on different cancer cell lines and on a normal cell line, they were tracked in vitro by fluorescence detection, and their uptake was evaluated by ICP-MS measurements.

Graphical abstract: Towards the elaboration of new gold-based optical theranostics

Supplementary files

Article information

Article type
Paper
Submitted
30 Sep 2014
Accepted
28 Nov 2014
First published
28 Nov 2014

Dalton Trans., 2015,44, 4874-4883

Towards the elaboration of new gold-based optical theranostics

P. Doulain, R. Decréau, C. Racoeur, V. Goncalves, L. Dubrez, A. Bettaieb, P. Le Gendre, F. Denat, C. Paul, C. Goze and E. Bodio, Dalton Trans., 2015, 44, 4874 DOI: 10.1039/C4DT02977A

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