Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 33, 2014
Previous Article Next Article

Pyrophosphate selective fluorescent chemosensors: cascade recognition of nuclear stain mimicking DAPI

Author affiliations

Abstract

A new zinc(II) complex with a condensed hydroxynaphthyl pyridine (SPHN) as the coordinated ligand has been synthesized for the selective recognition of pyrophosphate (PPi) over other anions including phosphate in a mixed aqueous solution. The fluorescence enhancement of SPHN in association with Zn2+ ions is quenched in the presence of intracellular pyrophosphate. This phenomenon is utilized in the construction of a logic gate. The binding of SPHN with Zn2+ and its displacement by PPi have been established by photophysical investigation and supported by the DFT level of studies. The development of blue fluorescence in the {SPNH–Zn} complex upon binding of zinc with SPHN is shown to be useful as a nucleus marker in a cell similar to the commercially available staining compound, DAPI (diamino-2-phenylindole).

Graphical abstract: Pyrophosphate selective fluorescent chemosensors: cascade recognition of nuclear stain mimicking DAPI

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 29 Apr 2014, accepted on 23 Jun 2014 and first published on 23 Jun 2014


Article type: Paper
DOI: 10.1039/C4DT01262C
Citation: Dalton Trans., 2014,43, 12689-12697
  •   Request permissions

    Pyrophosphate selective fluorescent chemosensors: cascade recognition of nuclear stain mimicking DAPI

    S. Goswami, A. K. Das, B. Pakhira, S. Basu Roy, A. K. Maity, P. Saha and S. Sarkar, Dalton Trans., 2014, 43, 12689
    DOI: 10.1039/C4DT01262C

Search articles by author