Jump to main content
Jump to site search

Issue 13, 2014
Previous Article Next Article

Macro-/micro-environment-sensitive chemosensing and biological imaging

Author affiliations

Abstract

Environment-related parameters, including viscosity, polarity, temperature, hypoxia, and pH, play pivotal roles in controlling the physical or chemical behaviors of local molecules. In particular, in a biological environment, such factors predominantly determine the biological properties of the local environment or reflect corresponding status alterations. Abnormal changes in these factors would cause cellular malfunction or become a hallmark of the occurrence of severe diseases. Therefore, in recent years, they have increasingly attracted research interest from the fields of chemistry and biological chemistry. With the emergence of fluorescence sensing and imaging technology, several fluorescent chemosensors have been designed to respond to such parameters and to further map their distributions and variations in vitro/in vivo. In this work, we have reviewed a number of various environment-responsive chemosensors related to fluorescent recognition of viscosity, polarity, temperature, hypoxia, and pH that have been reported thus far.

Graphical abstract: Macro-/micro-environment-sensitive chemosensing and biological imaging

Back to tab navigation

Publication details

The article was received on 29 Jan 2014 and first published on 10 Apr 2014


Article type: Review Article
DOI: 10.1039/C4CS00051J
Author version available: Download Author version (PDF)
Citation: Chem. Soc. Rev., 2014,43, 4563-4601
  •   Request permissions

    Macro-/micro-environment-sensitive chemosensing and biological imaging

    Z. Yang, J. Cao, Y. He, J. H. Yang, T. Kim, X. Peng and J. S. Kim, Chem. Soc. Rev., 2014, 43, 4563
    DOI: 10.1039/C4CS00051J

Search articles by author

Spotlight

Advertisements