Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 8, 2014
Previous Article Next Article

Fluorinated sulfoximines: syntheses, properties and applications

Author affiliations


The interest in fluorinated sulfoximines has rapidly increased over the past twenty years. As sulfoximines are analogues of sulfones where one of the two S[double bond, length as m-dash]O units has been replaced by an S[double bond, length as m-dash]N moiety, they can confer new reactivities and properties never observed for the respective sulfones. In this tutorial review, we present the specific properties of fluorinated sulfoximines (including important bioactivities) and describe the syntheses and the applications of fluoromethyl transfer agents such as Johnson's reagent. Furthermore, we highlight the exceptional electronic effects induced by the presence of strongly electron-withdrawing fluoro-bearing sulfonimidoyl moieties, which allowed the development of remarkable super-acidifiers and super-acceptors with relevance in materials sciences.

Graphical abstract: Fluorinated sulfoximines: syntheses, properties and applications

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 25 Nov 2013 and first published on 18 Feb 2014

Article type: Tutorial Review
DOI: 10.1039/C3CS60427F
Citation: Chem. Soc. Rev., 2014,43, 2426-2438
  •   Request permissions

    Fluorinated sulfoximines: syntheses, properties and applications

    V. Bizet, R. Kowalczyk and C. Bolm, Chem. Soc. Rev., 2014, 43, 2426
    DOI: 10.1039/C3CS60427F

Search articles by author