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Issue 8, 2014
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Three-dimensional nano-biointerface as a new platform for guiding cell fate

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Abstract

Three-dimensional nano-biointerface has been emerging as an important topic for chemistry, nanotechnology, and life sciences in recent years. Understanding the exchanges of materials, signals, and energy at biological interfaces has inspired and helped the serial design of three-dimensional nano-biointerfaces. The intimate interactions between cells and nanostructures bring many novel properties, making three-dimensional nano-biointerfaces a powerful platform to guide cell fate in a controllable and accurate way. These advantages and capabilities endow three-dimensional nano-biointerfaces with an indispensable role in developing advanced biological science and technology. This tutorial review is mainly focused on the recent progress of three-dimensional nano-biointerfaces and highlights the new explorations and unique phenomena of three-dimensional nano-biointerfaces for cell-related fundamental studies and biomedical applications. Some basic bio-inspired principles for the design and creation of three-dimensional nano-biointerfaces are also delivered in this review. Current and further challenges of three-dimensional nano-biointerfaces are finally addressed and proposed.

Graphical abstract: Three-dimensional nano-biointerface as a new platform for guiding cell fate

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Publication details

The article was received on 18 Nov 2013 and first published on 06 Feb 2014


Article type: Tutorial Review
DOI: 10.1039/C3CS60419E
Citation: Chem. Soc. Rev., 2014,43, 2385-2401
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    Three-dimensional nano-biointerface as a new platform for guiding cell fate

    X. Liu and S. Wang, Chem. Soc. Rev., 2014, 43, 2385
    DOI: 10.1039/C3CS60419E

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