Issue 86, 2014

Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

Abstract

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

Graphical abstract: Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

Supplementary files

Article information

Article type
Communication
Submitted
29 Jul 2014
Accepted
09 Sep 2014
First published
09 Sep 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 13157-13160

Author version available

Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

D. J. Nieves, N. S. Azmi, R. Xu, R. Lévy, E. A. Yates and D. G. Fernig, Chem. Commun., 2014, 50, 13157 DOI: 10.1039/C4CC05909C

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