Issue 75, 2014
From the journal:

Chemical Communications

Nanometer-sized manganese oxide-quenched fluorescent oligonucleotides: an effective sensing platform for probing biomolecular interactions†

Dinggeng He,a   Xiaoxiao He,*a   Kemin Wang,*a   Xue Yang,a   Xiaoxiao Yang,a   Xuecai Lia  and  Zhen Zoua  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Institute of Biology, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China
E-mail: kmwang@hnu.edu.cn, xiaoxiaohe@hnu.edu.cn

Abstract

We propose a novel template-assisted strategy to prepare nanometer-sized manganese oxide (nano-MnO2) by self-assembly of some MnO2 platelets and demonstrate its application as a new class of biosensing platform for probing DNA hybridization and aptamer–target interaction in a homogeneous solution.

Graphical abstract: Nanometer-sized manganese oxide-quenched fluorescent oligonucleotides: an effective sensing platform for probing biomolecular interactions

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Article information

DOI
https://doi.org/10.1039/C4CC04573D
Article type
Communication
Submitted
16 Jun 2014
Accepted
31 Jul 2014
First published
31 Jul 2014

Chem. Commun., 2014,50, 11049-11052

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Nanometer-sized manganese oxide-quenched fluorescent oligonucleotides: an effective sensing platform for probing biomolecular interactions

D. He, X. He, K. Wang, X. Yang, X. Yang, X. Li and Z. Zou, Chem. Commun., 2014, 50, 11049 DOI: 10.1039/C4CC04573D

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