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Issue 82, 2014
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Aptamer-based cell imaging reagents capable of fluorescence switching

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Abstract

We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

Graphical abstract: Aptamer-based cell imaging reagents capable of fluorescence switching

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Publication details

The article was received on 21 May 2014, accepted on 21 Aug 2014 and first published on 22 Aug 2014


Article type: Communication
DOI: 10.1039/C4CC03888F
Citation: Chem. Commun., 2014,50, 12329-12332
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    Aptamer-based cell imaging reagents capable of fluorescence switching

    Y. K. Jung, M. Woo, H. T. Soh and H. G. Park, Chem. Commun., 2014, 50, 12329
    DOI: 10.1039/C4CC03888F

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