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Issue 56, 2014
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Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

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Abstract

Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products.

Graphical abstract: Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

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Publication details

The article was received on 08 Apr 2014, accepted on 21 May 2014 and first published on 21 May 2014


Article type: Communication
DOI: 10.1039/C4CC02604G
Citation: Chem. Commun., 2014,50, 7548-7551
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    Separation and enrichment of enantiopure from racemic compounds using magnetic levitation

    X. Yang, S. Y. Wong, D. K. Bwambok, M. B. J. Atkinson, X. Zhang, G. M. Whitesides and A. S. Myerson, Chem. Commun., 2014, 50, 7548
    DOI: 10.1039/C4CC02604G

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